Advil Gel Caplets deliver effective pain relief that lasts for hours. Advil is a safe and effective pain reliever. For over 30 years, patients and doctors have trusted Advil to treat many kinds of acute pain, including headache relief, muscle aches, menstrual cramps, minor arthritis, joint pain, and backache. Use as directed. Any medication may cause side effects. You should not take more than the recommended dose because it will increase the risk of side effects. To maximize the benefit and reduce risk, it is important to use over-the-counter medicines responsibly according to the label and speak with a doctor or pharmacist if you have any questions.